Saturday, December 1, 2012

Official: Hamas leader Mashaal set to visit Gaza

GAZA CITY, Gaza Strip (AP) ? A senior Hamas official in Gaza says the Islamic militant group's leader is poised to pay his first visit ever to the coastal strip.

Khaled Mashaal is set to visit Gaza next week to mark the movement's 25th anniversary and congratulate its leaders and militants for battling Israel during a recent 8-day offensive.

Mashaal was previously prevented from crossing into Gaza by longtime Egyptian leader Hosni Mubarak. Hamas says it is coordinating the visit with Egypt's new Muslim Brotherhood leaders.

The official, who spoke anonymously Saturday, citing security concerns, called the visit "historic."

Hamas violently overtook Gaza from forces loyal to Palestinian President Mahmoud Abbas' Fatah party in 2007. It has yet to reconcile with Fatah, which rules the West Bank.

Until recently, Mashaal had been based in Syria.

Source: http://news.yahoo.com/official-hamas-leader-mashaal-set-visit-gaza-111304240.html

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Army GI in WikiLeaks case takes stand at hearing

FORT MEADE, Md. (AP) ? An Army private charged in the biggest security breach in U.S. history took the stand Thursday at a military hearing about what he contends was needlessly harsh treatment at a Marine Corps brig.

Pfc. Bradley Manning testified on the third day of a pretrial hearing at Fort Meade, outside Baltimore.

Wearing his dress uniform, he appeared nervous, stuttering over his words as he tried to answer questions from a defense attorney about his arrest in Baghdad in May 2010. He was testifying only about his arrest and confinement.

Seated in the witness booth, he swiveled back and forth and gestured with his hands as he described the layout of his confinement quarters overseas.

Manning is trying to avoid trial in the WikiLeaks case. He argues he was punished enough when he was locked up alone in a small cell for nearly nine months at a brig in Quantico, Va., and had to sleep naked for several nights.

The military contends the treatment was proper, given Manning's classification then as a maximum-security detainee who posed a risk of injury to himself or others.

Earlier Thursday, a military judge accepted the terms under which Manning would plead guilty to eight charges for sending classified documents to the secret-spilling WikiLeaks website.

Col. Denise Lind's ruling doesn't mean the pleas have been formally accepted. That could happen in December.

But Lind approved the language of the offenses to which Manning would admit.

She said those offenses carry a total maximum prison term of 16 years.

Manning made the offer as a way of accepting responsibility for the leak. Government officials have not said whether they would continue prosecuting him for the other 14 counts he faces, including aiding the enemy. That offense carries a maximum penalty of life in prison.

Under the proposal, Manning would admit to willfully sending the following material: a battlefield video file, some classified memos, more than 20 Iraq war logs, more than 20 Afghanistan war logs and other classified materials. He would also plead guilty to wrongfully storing classified information.

Meanwhile, Manning's lawyers are arguing that the charges against the soldier should be dismissed because of how he was treated while confined at Quantico.

Other prospective witnesses include a military psychiatrist who examined Manning at Quantico, and the former commander of the confinement facility at Fort Leavenworth, Kan. Manning was later moved there, re-evaluated and given a medium-security classification.

Source: http://news.yahoo.com/army-gi-wikileaks-case-takes-stand-hearing-190359537.html

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Friday, November 30, 2012

Train derailment sends chemical tankers into N.J. creek

PAULSBORO, N.J. (AP) ? Authorities say only one of the derailed train cars in southern New Jersey has leaked hazardous material.

The Department of Environmental Protection says the car leaked vinyl chloride as a gas and all of it has since dissipated.

The chemical can cause nausea and breathing problems.

Several tanker cars derailed in the accident Friday morning on a rail bridge in Paulsboro and toppled into a creek. Part of the bridge has buckled but the full extent of the damage is not yet known.

Officials at Underwood-Memorial Hospital say 11 people have been transported with complaints related to the derailment and five more arrived on their own. The hospital's communication's office says all are believed to have complained of having respiratory problems.

Residents in three towns were told to stay inside after the derailment.

The cause of the accident hasn't been determined.

Source: http://news.yahoo.com/derailment-sends-chemical-tank-cars-nj-creek-131625119.html

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Proteins that work at the ends of DNA could provide cancer insight

ScienceDaily (Nov. 29, 2012) ? New insights into a protein complex that regulates the very tips of chromosomes could improve methods of screening anti-cancer drugs.

Led by bioengineering professor Sua Myong, the research group's findings are published in the journal Structure.

Myong's group focused on understanding the proteins that protect and regulate telomeres, segments of repeating DNA units that cap the ends of chromosomes. Telomeres protect the important gene-coding sections of DNA from loss or damage, the genetic equivalent of aglets -- the covering at the tips of shoelaces that keep the ends of the laces from unraveling or fraying.

Telomeres play an important role in cell aging and death, since each time a cell divides, a little bit is lost from the end of the telomere. Thus, cell biologists postulate that telomere length can determine the lifespan of a cell. Cancer cells, however, have a way to get around this limitation: An enzyme called telomerase that adds length to telomeres is highly active in cancer cells. This allows cancer cells to divide in perpetuity, running amok through tissues and systems.

"Cancer researchers want to get a hold of this problem, control this indefinite lengthening of the telomeres," said Myong, who also is affiliated with the Institute for Genomic Biology at the U. of I. "A lot of the anti-cancer drugs are targeted directly to these telomeres so that they can inhibit telomerase activity. The proteins we study regulate the activity of telomerase."

Using a technique developed at Illinois that allows researchers to watch single molecules interact in real time, Myong's group determined how two proteins called POT-1 and TTP-1 bind to the telomere. POT-1 protects the fragile telomere ends from being attacked by other regulatory proteins that might mistake the end for a broken or damaged area of DNA. When POT-1 and TTP-1 work together in a complex, they promote telomerase activity, an interesting target for cancer researchers.

The group found that on its own, POT-1 binds to the folded-up telomere in distinct steps at particular points in the telomere's DNA sequence, unfolding the telomere in a stepwise manner. However, the POT-1/TTP-1 complex surprised the researchers by binding, then freely sliding back and forth along the telomere end.

"Instead of stepwise binding, what we saw was a mobile protein complex, a dynamic sliding motion," Myong said. "Somehow it was as if the static binding activity of POT-1 is completely lost -- the protein complex just slid back and forth. We were able to reproduce the data and confirm it with many different tail lengths of the telomeric DNA and we know now that the contact between POT-1 and the telomere is somehow altered when the partner protein comes and binds."

Next, the researchers will add telomerase and see how the sliding activity of the POT-1/TTP-1 complex affects telomerase activity. Myong postulates that the sliding may promote telomerase activity -- and thus telomere lengthening -- by making the end of the telomere accessible for the telomerase enzyme to bind.

"We are excited about the possibility that this kind of mobility can increase the telomerase extension activity," Myong said. "It's somehow engaging the enzyme so that it can stay bound to the DNA longer. So it must involve a direct interaction."

Ultimately, understanding the POT-1/TTP-1 complex gives drug developers a new target for anti-cancer drugs, and the assay Myong's group used to monitor the complex could offer a venue for evaluating telomere-targeting drugs.

"We want to extend our a basic science knowledge in telomere biology into causes of cancer and we hope that our assay can be useful for telomere-targeted drug screening," Myong said.

The American Cancer Society and the Human Frontier Science Research Program supported this work.

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Story Source:

The above story is reprinted from materials provided by University of Illinois at Urbana-Champaign.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Helen Hwang, Noah Buncher, Patricia?L. Opresko, Sua Myong. POT1-TPP1 Regulates Telomeric Overhang Structural Dynamics. Structure, 2012; 20 (11): 1872 DOI: 10.1016/j.str.2012.08.018

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/H7VyF-YvzO4/121129152029.htm

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Two winners in record Powerball jackpot

Winning tickets for the record Powerball jackpot worth more than $587 million were purchased in Arizona and Missouri.

Missouri Lottery official Susan Goedde confirmed to ABC News this morning that one of the winning tickets was purchased in the state, but they would not be announcing a town until later this morning.

Arizona lottery officials said they had no information on that state's winner or winners but would announce where it was sold during a news conference later in the day.

The winning numbers for the jackpot were 5, 23, 16, 22 and 29. The Powerball was 6.

The jackpot swelled to $587.5 million, according to Lottery official Sue Dooley. The two winners will split the jackpot each getting $293.75 million.

An additional 8,924,123 players won smaller prizes, according to Powerball's website.

"There were 58 winners of $1 million and there were eight winners of $2 million. So a total of $74 million," said Chuck Strutt, Director of the Multi-State Lottery Association.

In Photos: Biggest Lotto Jackpot Winners

Hopeful players bought tickets at the rate of 131,000 every minute up until an hour before the deadline of 11 p.m. ET, according to lottery officials.

The jackpot had already rolled over 16 consecutive times without a winner. That fact, plus the doubling in price of a Powerball ticket, accounted for the unprecedented richness of the pot.

"Back in January, we moved Powerball from being a $1 game to $2," said Mary Neubauer, a spokeswoman at the game's headquarters in Iowa. "We thought at the time that this would mean bigger and faster-growing jackpots."

That proved true. The total, she said, began taking "huge jumps -- another $100 million since Saturday." It then jumped another $50 million.

The biggest Powerball pot on record until now -- $365 million -- was won in 2006 by eight Lincoln, Neb., co-workers. As the latest pot swelled, lottery officials said they began getting phone calls from all around the world.

"When it gets this big," said Neubauer, "we get inquiries from Canada and Europe from people wanting to know if they can buy a ticket. They ask if they can FedEx us the money."

The answer she has to give them, she said, is: "Sorry, no. You have to buy a ticket in a member state from a licensed retail location."

About 80 percent of players don't choose their own Powerball number, opting instead for a computer-generated one. Asked if there's anything a player can do to improve his or her odds of winning, Neubauer said there isn't -- apart from buying a ticket, of course.

Lottery officials put the odds of winning this Powerball pot at one in 175 million, meaning you'd have been 25 times more likely to win an Academy Award.

Skip Garibaldi, a professor of mathematics at Emory University in Atlanta, provided additional perspective: You are three times more likely to die from a falling coconut, he said; seven times more likely to die from fireworks, "and way more likely to die from flesh-eating bacteria" (115 fatalities a year) than you are to win the Powerball lottery.

Segueing, then, from death to life, Garibaldi noted that even the best physicians, equipped with the most up-to-date equipment, can't predict the timing of a child's birth with much accuracy.

"But let's suppose," he said, "that your doctor managed to predict the day, the hour, the minute and the second your baby would be born."

The doctor's uncanny prediction would be "at least 100 times" more likely than your winning.

Even though he knows the odds all too well, Garibaldi said he usually plays the lottery.

When it gets this big, I'll buy a couple of tickets," he said. "It's kind of exciting. You get this feeling of anticipation. You get to think about the fantasy."

So, did he buy two tickets this time?

"I couldn't," he told ABC News. "I'm in California" -- one of eight states that doesn't offer Powerball.

In case you were wondering, this Saturday's Powerball jackpot is starting at $40 million.

ABC News Radio contributed to this report.

Also Read

Source: http://gma.yahoo.com/winning-powerball-tickets-jackpot-sold-ariz-mo-065718021--abc-news-topstories.html

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Thursday, November 29, 2012

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Installed price of solar photovoltaic systems in US continues to decline at rapid pace

ScienceDaily (Nov. 27, 2012) ? The installed price of solar photovoltaic (PV) power systems in the United States fell substantially in 2011 and through the first half of 2012, according to the latest edition of Tracking the Sun, an annual PV cost-tracking report produced by the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab).

The median installed price of residential and commercial PV systems completed in 2011 fell by roughly 11 to 14 percent from the year before, depending on system size, and, in California, prices fell by an additional 3 to 7 percent within the first six months of 2012. These recent installed price reductions are attributable, in large part, to dramatic reductions in PV module prices, which have been falling precipitously since 2008.

The report indicates that non-module costs -- such as installation labor, marketing, overhead, inverters, and the balance of systems -- have also fallen significantly over time. "The drop in non-module costs is especially important," notes report co-author Ryan Wiser of Berkeley Lab's Environmental Energy Technologies Division, "as these costs can be most readily influenced by local, state, and national policies aimed at accelerating deployment and removing market barriers." According to the report, average non-module costs for residential and commercial systems declined by roughly 30 percent from 1998 to 2011, but have not declined as rapidly as module prices in recent years. As a result, non-module costs now represent a sizable fraction of the installed price of PV systems, and continued deep reduction in the price of PV will require concerted emphasis on lowering the portion of non-module costs associated with so-called "business process" or "soft" costs.

The report indicates that the median installed price of PV systems installed in 2011 was $6.10 per watt (W) for residential and small commercial systems smaller than 10 kilowatts (kW) in size and was $4.90/W for larger commercial systems of 100 kW or more in size. Utility-sector PV systems larger than 2,000 kW in size averaged $3.40/W in 2011. Report co-author Galen Barbose, also of Berkeley Lab, stresses the importance of keeping these numbers in context, noting that "these data provide a reliable benchmark for systems installed in the recent past, but prices have continued to decline over time, and PV systems being sold today are being offered at lower prices."

Based on these data and on installed price data from other major international PV markets, the authors suggest that PV prices in the United States may be driven lower through large-scale deployment programs, but that other factors are also important in achieving installed price reductions.

The market for solar PV systems in the United States has grown rapidly over the past decade, as national, state and local governments offered various incentives to expand the solar market and accelerate cost reductions. This fifth edition in Berkeley Lab's Tracking the Sun reportseries describes historical trends in the installed price of PV in the United States, and examines more than 150,000 residential, commercial, and utility-sector PV systems installed between 1998 and 2011 across 27 states, representing roughly 76 percent of all grid-connected PV capacity installed in the United States. Na?m Darghouth, also with Berkeley Lab, explains that "the study is intended to provide policy makers and industry observers with a reliable and detailed set of historical benchmarks for tracking and understanding past trends in the installed price of PV."

Prices Differ by Region and by Size and Type of System

The study also highlights the significant variability in PV system pricing, some of which is associated with differences in installed prices by region and by system size and installation type. Comparing across U.S. states, for example, the median installed price of PV systems less than 10 kW in size that were completed in 2011 and ranged from $4.90/W to $7.60/W, depending on the state.

It also shows that PV installed prices exhibit significant economies of scale. Among systems installed in 2011, the median price for systems smaller than 2 kW was $7.70/W, while the median price for large commercial systems greater than 1,000 kW in size was $4.50/W. Utility-scale systems installed in 2011 registered even lower prices, with most systems larger than 10,000 kW ranging from $2.80/W to $3.50/W.

The report also finds that the installed price of residential PV systems on new homes has generally been significantly lower than the price of similarly sized systems installed as retrofits to existing homes, that building integrated PV systems have generally been higher priced than rack-mounted systems, and that systems installed on tax-exempt customer sites have generally been priced higher than those installed at residential and for-profit commercial customer sites.

Price Declines for PV System Owners in 2011 Were Offset by Falling Incentives

State agencies and utilities in many regions offer rebates or other forms of cash incentives for residential and commercial PV systems. According to the report, the median pre-tax value of such cash incentives ranged from $0.90/W to $1.20/W for systems installed in 2011, depending on system size. These incentives have declined significantly over time, falling by roughly 80 percent over the past decade, and by 21 percent to 43 percent from just 2010 to 2011. Rather than a direct cash incentive, some states with renewables portfolio standards provide financial incentives for solar PV by creating a market for solar renewable energy certificates (SRECs), and SREC prices have also fallen dramatically in recent years. These declines in cash incentives and SREC prices have, to a significant degree, offset recent installed price reductions, dampening any overall improvement in the customer economics of solar PV.

The report Tracking the Sun V: An Historical Summary of the Installed Price of Photovoltaics in the United States from 1998 to 2011, by Galen Barbose, Na?m Darghouth, and Ryan Wiser, may be downloaded from: http://emp.lbl.gov/sites/all/files/LBNL-5919e-REPORT.pdf.

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The above story is reprinted from materials provided by DOE/Lawrence Berkeley National Laboratory.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/AbBJiWU30oQ/121127130258.htm

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